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Rice Bran Extract Suppresses High-Fat Diet-Induced Hyperlipidemia and Hepatosteatosis through Targeting AMPK and STAT3 Signaling.
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Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis.
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Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation.
EXPERIMENTAL AND MOLECULAR MEDICINE.
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Structural mechanism for regulation of Rab7 by site-specific monoubiquitination.
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In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate.
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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
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mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.
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The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway.
EBIOMEDICINE.
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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
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Brown fat organogenesis and maintenance requires AKT1 and AKT2.
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A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells.
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Insulin PACS a Punch in SIRT1 Activity.
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A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1.
NATURE CELL BIOLOGY.
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The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.
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The deubiquitinating enzyme, ubiquitin-specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein.
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